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Information about Naltrexone.
It is important for you to keep a written list of all of the prescription and nonprescriptionover-the-countermedicines you are takingas well as any products such as vitaminsmineralsor other dietary supplementsYou should bring this list with you each time you visit a doctor or if you are admitted to a hospitalIt is also important information to carry with you in case of emergencies.
REVIA is a pure opioid antagonistIt does not lead to physical or psychological dependenceTolerance to the opioid antagonist effect is not known to occur.
Although no causal relationship with REVIA is suspectedphysicians should be aware that treatment with REVIA does not reduce the risk of suicide in these patientssee PRECAUTIONS
Before having any laboratory teststell your doctor and the laboratory personnel that you are taking naltrexone.
Cases of hepatitis and clinically significant liver dysfunction were observed in association with REVIA exposure during the clinical development program and in the postmarketing periodTransientasymptomatic hepatic transaminase elevations were also observed in the clinical trials and postmarketing periodWhen patients presented with elevated transaminasesthere were often other potential causative or contributory etiologies identifiedincluding pre-existing alcoholic liver diseasehepatitis B and/or C infectionand concomitant usage of other potentially hepatotoxic drugsAlthough clinically significant liver dysfunction is not typically recognized as a manifestation of opioid withdrawalopioid withdrawal that is precipitated abruptly may lead to systemic sequelaeincluding acute liver injury.
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