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Unlike other cholesterol lowering medicines, known as statins, zetia works in the digestive tract by blocking the absorption of cholesterol that you derive from food.

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From this studyit may be concluded that addition of ezetimibe has incremental effects on LDL cholesterol reductionIn patients with a high risk of hepatic insufficiencythe addition of ezetimibe to the lowest dose of lovastatin may be helpful in preventing adverse effects of high-dose lovastatin while gaining the full benefits of high-dose lovastatinAlsothe combination of ezetimibe and lovastatin has no greater adverse effects than lovastatin monotherapy7

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Ezetimibe’s mechanism of action involves reducing blood cholesterol by inhibiting the absorption of cholesterol in the small intestineUnlike other cholesterol-reducing agentsezetimibe localizes and appears to act at the brush border of the small intestine and inhibits the absorption of cholesterolleading to a decrease in the delivery of intestinal cholesterol to the liverThis leads to a reduction of hepatic cholesterol stores and an increase in clearance of cholesterol from the bloodEzetimibe has been demonstrated to have no significant effect on the plasma concentrations of the fat-soluble vitamins ADand E3

Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use Zetia only for the indication prescribed.

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more than 25,000 people are in studies testing zetia now, and independent monitors have found no problems that would lead them to stop the trials.

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