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Let patients know that antacids may be used while taking NEXIUMAdvise patients to take NEXIUM at least one hour before a mealFor patients who are prescribed NEXIUM Delayed-Release Capsulesadvise them not to chew or crush the capsulesAdvise patients thatif they open NEXIUM Delayed-Release Capsules to mix the granules with foodthe granules should only be mixed with applesauceUse with other foods has not been evaluated and is not recommendedFor patients who are advised to open the NEXIUM Delayed-Release Capsules before taking them or who are prescribed NEXIUM For Delayed-Release Oral Suspensioninstruct them in the proper technique for administrationsee DOSAGE AND ADMINISTRATIONand tell them to follow the dosing instructions in the PATIENT INFORMATION insert included in the packageInstruct patients to rinse the syringe with water after each useFor patients who are prescribed NEXIUM For Delayed-Release Oral Suspension and need to use more than one packet for their doseinstruct them regarding the correct amount of water to use when mixing their dose.

Ask a doctor before using this medicine if you are pregnant or breast-feeding.

Drugs which induce CYP2C19 or CYP3A4such as StJohn’s Wort or rifampincan substantially decrease esomeprazole concentrationssee DRUG INTERACTIONSAvoid concomitant use of NEXIUM with StJohn’s Wort or rifampin.

Nexiumesomeprazole magnesiumis a proton pump inhibitor that decreases the amount of acid produced in the stomach.

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relief of symptoms with nexium esomeprazole does not rule out the existence of other serious stomach conditions.

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