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Renal function can deteriorate if potentially nephrotoxic drugse.gaminoglycosidescephalosporinsfurosemideare given simultaneously and also in patients whose renal function is already impairedRenal function must be monitored carefully in such cases and if deterioration is found discontinuation of the treatment should be consideredsee section 4.4

In the event of surgical intervention during treatmentadministration of nimodipine should be continueddose as abovefor at least five days.

Animal studies have shown that when nimodipine and zidovudine are administered concomitantlythe AUC for zidovudine was increasedand the volume of distribution and clearance rate decreasedThe clinical relevance of this interaction is unknownbut since the side-effect profile of zidovudine is known to be dose relatedthis interaction should be considered in patients receiving nimodipine and zidovudine concomitantly.

There may be other drugs that can affect nimodipineresulting in side effects and/or reduced effectivenessTell your doctor about all the prescription and over-the-counter medications you useThis includes vitaminsmineralsherbal productsand drugs prescribed by other doctorsDo not start using a new medication without telling your doctor.

HIV/AIDS medicationatazanavircobicistatdelavirdinefosamprenavirindinavirnelfinavirritonavirsaquinavir.

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