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The safety and effectiveness of xalatan in children have not been established.

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Advise patients about the potential for increased brown pigmentation of the iriswhich may be permanentInform patients about the possibility of eyelid skin darkeningwhich may be reversible after discontinuation of XALATANsee WARNINGS AND PRECAUTIONS

It is not likely that other drugs you take orally or inject will have an effect on latanoprost used in the eyesBut many drugs can interact with each otherTell each of your healthcare providers about all medicines you useincluding prescription and over-the-counter medicinesvitaminsand herbal products.

Studies in man indicate that the peak concentration in the aqueous humour is reached about two hours after topical administrationAfter topical application in monkeyslatanoprost is distributed primarily in the anterior segmentthe conjunctivae and the eyelidsOnly minute quantities of the drug reach the posterior segment.

Skip the missed dose and use the medicine at the next regularly scheduled timeDo not use extra medicine to make up the missed dose.

It is not known whether this drug or its metabolites are excreted in human milkBecause many drugs are excreted in human milkcaution should be exercised when XALATAN is administered to a nursing woman.

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take out contact lenses before using xalatan.

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